Viimeksi syötetyt Väitöskirjat

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    • Ultrasensitive heterogeneous bioaffinity assays by eliminating nonspecific binding of upconverting nanoparticles 

      Kuusinen, Saara
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis F: Technica & Informatica : 55 (Turun yliopisto, 16.05.2025)
      Bioaffinity assays are commonly used for specific detection of biomarkers in biological samples. Reducing the lowest detectable concentration, i.e. the analytical sensitivity of such assays, is beneficial for several ...

    • Reverse shoulder arthroplasty – factors affecting clinical results and risk of revision 

      Lehtimäki, Kaisa
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis D: Medica - Odontologica : 1868 (Turun yliopisto, 25.04.2025)
      Reverse shoulder arthroplasty (RSA) is increasingly used to treat painful cuff tear arthropathy (CTA), shoulder osteoarthritis (OA), and proximal humeral fractures (PHF). This non-anatomical procedure, featuring a convex ...

    • Epigenetic regulation of bone formation - Effects of LSD1 and RCOR2 on osteoblast differentiation 

      Rummukainen, Petri
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis D: Medica - Odontologica : 1869 (Turun yliopisto, 09.05.2025)
      Bone remodelling is regulated by a complex network of pathways and factors where multiple cell types coordinate to maintain bone strength. Different regulatory mechanisms controlling the transcription of cell type specific ...

    • Optimizing polycrystalline silicon for energy-efficient radiofrequency devices with a multiscale simulation approach 

      Santonen, Mikael
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser AI: Astronomica - Chemica - Physica – Mathematica : 735 (Turun yliopisto, 09.05.2025)
      Increasing demand of applications involving high-frequency devices such as wireless communications exposes limitations, problems, and different sources of signal loss. These issues continue to provide interesting and ...

    • Gaining reliable endpoint awareness in a network security solution 

      Heino, Jenny
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis F: Technica & Informatica : 53 (Turun yliopisto, 09.05.2025)
      The field of network security has been going through a significant evolution during recent years. Services that used to be run locally by organizations, such as email servers and office solutions, have largely been transformed ...

    • Fostering inclusive innovations by using ICT to empower grassroots entrepreneurs in East Africa 

      Nkonoki, Emma
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis F: Technica & Informatica : 56 (Turun yliopisto, 25.04.2025)
      In the digital transformation era, inclusive innovations have become increasingly crucial with their exclusive role in bridging the socioeconomic gaps in emerging economies. This research study examines the role of Information ...

    • Tietovuodot kolmansille osapuolille suomalaisissa terveydenhuollon verkkopalveluissa 

      Rauti, Sampsa
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis F: Technica & Informatica : 54 (Turun yliopisto, 02.05.2025)
      Verkkosivustot ovat nykyään tärkeä työkalu monien kriittisten ja välttämättömien arkipäivän palvelujen tarjoamiseen. Verkkopalvelujen määrän kasvaessa ja käytön lisääntyessä yksityisyyskysymyksistäkin tulee entistä ...

    • The effects of acute exercise on immune cells in patients with cancer 

      Koivula, Tiia
      Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 1871 (Turun yliopisto, 02.05.2025)
      ABSTRACT Exercise has many systemic effects. Epidemiological studies suggest that exercise can improve the prognosis of people diagnosed with cancer, but the mechanisms are largely unknown. In animal models, exercise ...

    • Contaminants of emerging concern in Finnish waterbirds 

      Ask, Amalie Vigdel
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica - Odontologica : 417 (Turun yliopisto, 05.05.2025)
      Chemical pollution of the environment is widespread with detrimental effects on wildlife. Currently, more than 350 000 different chemicals or mixtures thereof are registered on the global market and the chemical industry ...

    • Combined PET-MRI and small bowel capsule endoscopy in diagnostics and surveillance of small bowel Crohn’s disease 

      Mattila, Juho
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica - Odontologica : 1865 (Turun yliopisto, 25.04.2025)
      Crohn’s disease (CD) is a chronic and relapsing inflammatory condition of the gut. Diagnostics of small bowel CD is difficult, as conventional endoscopy can only reach the proximal and distal ends of the small bowel. Cross ...

    • Somatic hypermutation targeting activity of proto-oncogenic enhancers 

      Soikkeli, Anni
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica - Odontologica : 1867 (Turun yliopisto, 02.05.2025)
      Somatic hypermutation (SHM) is an essential mechanism for the development of high-affinity antibodies. SHM occurs in germinal center B cells targeting antibody-coding immunoglobulin (Ig) genes to increase the affinity of ...

    • PhD-prepared nurses leading their careers 

      van Dongen, Lisa
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica - Odontologica : 1864 (Turun yliopisto, 25.04.2025)
      The aim of this study was to describe the careers of PhD-prepared nurses and analyse leadership practices in the careers as well as support sources for the careers. The first phase comprised the analytics of leadership ...

    • Risk factors of non-affective psychoses: Metabolic health indicators and physical activity in childhood and adolescence 

      Sormunen, Elina
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica - Odontologica : 1863 (Turun yliopisto, 25.04.2025)
      Psychoses are often considered the most severe psychiatric conditions, characterized by an impaired sense of reality. Schizophrenia is the most common and severe form of non-affective psychoses. In addition to psychiatric ...

    • Laatujohtaminen sosiaali- ja terveydenhuoltojärjestelmän muutoksessa 

      Friman, Susanna
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis D: Medica - Odontologica : 1859 (Turun yliopisto, 25.04.2025)
      Tutkimuksen tavoitteena oli tuottaa tietoa laadunhallinnan ja laatujohtamisen menettelyistä ja hyödyntämisestä sosiaali- ja terveydenhuollon kontekstissa palvelujärjestelmän rakenneuudistuksessa. I osatutkimuksen tavoitteena ...

    • Thigh muscle-tendon injuries in athletes: From the analysis of injury mechanisms to a novel diagnostic technique and surgical treatment 

      Jokela, Aleksi
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica - Odontologica : 1866 (Turun yliopisto, 04.04.2025)
      Thigh muscle-tendon injuries are common among athletes. These injuries can be severe and require long rehabilitation or even surgical treatment. They also tend to recur quite often, causing prolonged time off from sports. ...

    • Engineering lignocellulolytic enzymes for industrial applications: Engineering of laccase and endoglucanase 

      Nikoskelainen, Veera
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis F: Technica & Informatica : 52 (Turun yliopisto. Turun kauppakorkeakoulu, 11.04.2025)
      Energy consumption, especially electricity demand, is continually rising, while non-renewable fossil energy sources such as petroleum, natural gas, and coal are depleting. Fossil energy production also causes greenhouse ...

    • Alkuperäisyyden kaipuu ja alkukantaisuuden pelko: Kansa, luonto ja rodullistaminen Suomen modernissa taiteessa vuosina 1915–1930 

      Huusko, Timo
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser B: Humaniora : 713 (Turun yliopisto, 05.04.2025)
      Tutkin väitöskirjassani Suomen modernin taiteen kansankuvaa ja sen liittymistä käsityksiin suomalaisuuden olemuksesta vuosina 1915–1930. Suomessa vallitsi pitkään romantiikasta juontuva ajattelu, jossa alkuperäiseksi ...

    • Monoaminergic function and symptoms of Parkinson’s disease 

      Niemi, Kalle J.
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica - Odontologica : 1856 (Turun yliopisto, 11.04.2025)
      Parkinson’s disease is a common neurodegenerative movement disorder. The cardinal motor symptoms of Parkinson’s disease include bradykinesia, rigidity and rest tremor. The association between rest tremor and nigrostriatal ...

    • Intranasal dexmedetomidine in perioperative orthopedic anesthesia: Pharmacodynamic and harmacokinetic studies in adult patients 

      Tiainen, Suvi
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica - Odontologica : 1858 (Turun yliopisto, 04.04.2025)
      Effective pain management is critical to ensure optimal recovery after orthopedic procedures, but postoperative pain remains an issue despite the use of multimodal analgesia. Alpha-2-agonist dexmedetomidine could be a ...

    • The Prevalence and clinical significance of high bleeding risk in acute coronary syndromes 

      Kesti, Henri
      Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica - Odontologica : 1862 (Turun yliopisto, 11.04.2025)
      Major bleeding complications are common after acute coronary syndromes (ACS) and are associated with increased mortality. Thus, identification of high bleeding risk (HBR) patients during clinical decision making can be ...