Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion

Prudhomme M; Rainio EM; Koskinen PJ; Vahakoski RL; Anizon F; Sandholm JA; Santio NM; Virtanen SS; Moreau P
Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion

Prudhomme M
Rainio EM
Koskinen PJ
Vahakoski RL
Anizon F
Sandholm JA
Santio NM
Virtanen SS
Moreau P
Katso/Avaa
Lataukset: 

BIOMED CENTRAL LTD
doi:10.1186/1476-4598-9-279
Näytä kaikki kuvailutiedot
Julkaisun pysyvä osoite on:
https://urn.fi/URN:NBN:fi-fe2021042714234
Tiivistelmä
Conclusions: Altogether, our data indicate that DHPCC-9 is not only a powerful tool to investigate physiological effects of the oncogenic Pim family kinases, but also an attractive molecule for drug development to inhibit invasiveness of Pim-overexpressing cancer cells.
Kokoelmat