Schizophrenia polygenic risk score and long-term success in the labour market: A cohort study
Raitakari Olli T; Viinikainen Jutta; Kari Jaana T; Böckerman Petri; Hakulinen Christian; Lehtimäki Terho; Pehkonen Jaakko
Schizophrenia polygenic risk score and long-term success in the labour market: A cohort study
Raitakari Olli T
Viinikainen Jutta
Kari Jaana T
Böckerman Petri
Hakulinen Christian
Lehtimäki Terho
Pehkonen Jaakko
PERGAMON-ELSEVIER SCIENCE LTD
Julkaisun pysyvä osoite on:
https://urn.fi/URN:NBN:fi-fe2022081153935
https://urn.fi/URN:NBN:fi-fe2022081153935
Tiivistelmä
Employment is rare among people with a schizophrenia diagnosis. Meanwhile, a genetic liability for schizophrenia may hinder labour market performance. We studied how the polygenic risk score (PGS) for schizophrenia related to education and labour market outcomes. We found that a higher PGS was linked to lower educational levels and weaker labour market outcomes as well as a higher likelihood of receiving social income transfers, particularly among men. Assuming that the link is causal, our results indicate that individuals with schizophrenia or schizophrenia-related traits have a weakened ability to fully participate in the labour market, potentially reinforcing social exclusion.
Kokoelmat
- Rinnakkaistallenteet [19207]