Health-related qualify of life, angina type and coronary artery disease in patients with stable chest pain
Juhani Knuuti; William Hollingworth; Filip Adjić; Andrejs Erglis; Vasco Gama-Ribeiro; Marco Francone; Konrad Neumann; Gershan Davis; Béla Merkely; Matthias Gutberlet; Ioana Rodean; Henryk Dreger; Pál Maurovich-Horvat; Rita Faria; Peter Ball; Massimo Mancone; Paolo Ibes; Nina Rieckmann; Daniel Preuß; Adriane Napp; Ignacio Diez; Jacqueline Müller-Nordhorn; Theodora Benedek; José Rodriguez-Palomares; Marina Berzina; Josef Veselka; Mark Hensey; Patrick Donnelly; Bruno Loi; Tomasz Harań; Fabian Plank; Iñaki Gutiérrez-Ibarluzea; Mariusz Kruk; Audrone Vaitiekiene; Gudrun Feuchtner; Erica Thwaite; Laura Zajanckauskiene; Michael Woinke; Klaus F. Kofoed; Thomas Zelesny; Cezary Kępka; Damien Collison; Balasz Ruzsics; Stephen Schröder; Nada Čemerlić Adjić; Aleksandar N. Neskovic; Luca Saba; Thomas Engstrøm; Michael Fisher; Sarah Feger; Vojtěch Suchánek; Imre Benedek; Bruno Garcia del Blanco; Marc Dewey; Malgorzata Ilnicka Suckiel; Mihaela Ratiu; Radosav Vidakovic; Antti Saraste; Iñigo Lecumberri; Jonathan D. Dodd; Katriona Brooksbank
Health-related qualify of life, angina type and coronary artery disease in patients with stable chest pain
Juhani Knuuti
William Hollingworth
Filip Adjić
Andrejs Erglis
Vasco Gama-Ribeiro
Marco Francone
Konrad Neumann
Gershan Davis
Béla Merkely
Matthias Gutberlet
Ioana Rodean
Henryk Dreger
Pál Maurovich-Horvat
Rita Faria
Peter Ball
Massimo Mancone
Paolo Ibes
Nina Rieckmann
Daniel Preuß
Adriane Napp
Ignacio Diez
Jacqueline Müller-Nordhorn
Theodora Benedek
José Rodriguez-Palomares
Marina Berzina
Josef Veselka
Mark Hensey
Patrick Donnelly
Bruno Loi
Tomasz Harań
Fabian Plank
Iñaki Gutiérrez-Ibarluzea
Mariusz Kruk
Audrone Vaitiekiene
Gudrun Feuchtner
Erica Thwaite
Laura Zajanckauskiene
Michael Woinke
Klaus F. Kofoed
Thomas Zelesny
Cezary Kępka
Damien Collison
Balasz Ruzsics
Stephen Schröder
Nada Čemerlić Adjić
Aleksandar N. Neskovic
Luca Saba
Thomas Engstrøm
Michael Fisher
Sarah Feger
Vojtěch Suchánek
Imre Benedek
Bruno Garcia del Blanco
Marc Dewey
Malgorzata Ilnicka Suckiel
Mihaela Ratiu
Radosav Vidakovic
Antti Saraste
Iñigo Lecumberri
Jonathan D. Dodd
Katriona Brooksbank
BMC
Julkaisun pysyvä osoite on:
https://urn.fi/URN:NBN:fi-fe2021042825932
https://urn.fi/URN:NBN:fi-fe2021042825932
Tiivistelmä
Background Health-related quality of life (HRQoL) is impaired in patients with stable angina but patients often present with other forms of chest pain. The aim of this study was to compare the pre-diagnostic HRQoL in patients with suspected coronary artery disease (CAD) according to angina type, gender, and presence of obstructive CAD. Methods From the pilot study for the European DISCHARGE trial, we analysed data from 24 sites including 1263 patients (45.9% women, 61.1 +/- 11.3 years) who were clinically referred for invasive coronary angiography (ICA; 617 patients) or coronary computed tomography angiography (CTA; 646 patients). Prior to the procedures, patients completed HRQoL questionnaires: the Short Form (SF)-12v2, the EuroQoL (EQ-5D-3 L) and the Hospital Anxiety and Depression Scale. Results Fifty-five percent of ICA and 35% of CTA patients had typical angina, 23 and 33% had atypical angina, 18 and 28% had non-anginal chest discomfort and 5 and 5% had other chest discomfort, respectively. Patients with typical angina had the poorest physical functioning compared to the other angina groups (SF-12 physical component score; 41.2 +/- 8.8, 43.3 +/- 9.1, 46.2 +/- 9.0, 46.4 +/- 11.4, respectively, all age and gender-adjusted p < 0.01), and highest anxiety levels (8.3 +/- 4.1, 7.5 +/- 4.1, 6.5 +/- 4.0, 4.7 +/- 4.5, respectively, all adjusted p < 0.01). On all other measures, patients with typical or atypical angina had lower HRQoL compared to the two other groups (all adjusted p < 0.05). HRQoL did not differ between patients with and without obstructive CAD while women had worse HRQoL compared with men, irrespective of age and angina type. Conclusions Prior to a diagnostic procedure for stable chest pain, HRQoL is associated with chest pain characteristics, but not with obstructive CAD, and is significantly lower in women.
Kokoelmat
- Rinnakkaistallenteet [19207]