Retrospective observational analysis of a coronary artery bypass grafting surgery patient cohort: Off-pump versus on-pump

Abstract

<h3>Objectives</h3><p>To determine whether surgical technique has an effect on prognosis in coronary artery bypass grafting (CABG).</p><h3>Design</h3><p>Retrospective observational.</p><h3>Setting</h3><p>Single center.</p><h3>Participants</h3><p>All the off-pump (OPCABG) and on-pump (ONCABG) patients at Turku University Central Hospital in 2018.</p><h3>Interventions</h3><p>None.</p><h3>Measurements and main results</h3><p>After propensity score matching, perioperative, 1-year and 3-year mortality did not differ between the groups. The ONCABG patients received more allogenic red blood cells (1.3 vs. 0.6 units, p = 0.020), autologous red blood cells (564 vs. 285 ml, p < 0.001) and crystalloids (3388 vs. 2808 ml, p < 0.001), and had higher postoperative values of troponin T (581 vs. 222, p = 0.001) and lactate (1.69 vs. 1.23, p < 0.001) than the OPCABG patients.</p><h3>Conclusions</h3><p>The both techniques seem equally safe. However, there may be some benefits to avoiding using a heart-lung machine, such as lower infused fluid volumes. Myocardial damage may also be milder and postoperative hemodynamics more balanced in OPCABG patients, based on lower levels of troponin T and lactate.</p>