Trajectories of Interleukin 10 and Heart Fatty Acid-Binding Protein Levels in Traumatic Brain Injury Patients with or without Extracranial Injuries
Niiranen, Toni (2023-01-08)
Trajectories of Interleukin 10 and Heart Fatty Acid-Binding Protein Levels in Traumatic Brain Injury Patients with or without Extracranial Injuries
(08.01.2023)
Julkaisu on tekijänoikeussäännösten alainen. Teosta voi lukea ja tulostaa henkilökohtaista käyttöä varten. Käyttö kaupallisiin tarkoituksiin on kielletty.
suljettu
Julkaisun pysyvä osoite on:
https://urn.fi/URN:NBN:fi-fe202301162970
https://urn.fi/URN:NBN:fi-fe202301162970
Tiivistelmä
IL-10 and H-FABP have gained interest as diagnostic biomarkers of traumatic brain injury and our aim of the study is to investigate if there is a correlation between the levels of IL-10 and H-FABP with the levels of C-reactive protein and leukocytes and if there is a correlation between the admission level of H-FABP with admission levels of cardiac injury markers. We also investigate the trajectories of IL-10 and H-FABP between traumatic brain injury patients with and without extracranial injuries.
Our results indicate that inflammatory reactions during the early days after traumatic brain injury do not significantly confound the use of IL-10 or H-FABP as possible biomarkers. On the other hand, extracranial injuries seems to affect the levels of H-FABP. Further studies with larger study cohorts on these topics are needed.
Our results indicate that inflammatory reactions during the early days after traumatic brain injury do not significantly confound the use of IL-10 or H-FABP as possible biomarkers. On the other hand, extracranial injuries seems to affect the levels of H-FABP. Further studies with larger study cohorts on these topics are needed.